The Diagnostic Value of Electron Microscopy

Diagnostic Transmission Electron Microscopy

The high resolution and sensitivity of electron microscopy is still a valuable tool, and for some diseases it is the gold standard in pathological diagnosis. Today the sample turnaround time for processing in the lab can be significantly reduced from days to hours by the microwave technology. In urgent clinical cases, microwaveassisted tissue processing, in combination with digital image acquis...

Electron Microscopy of Fowl Pox Virus

Examination of Lung Parenchyma by Electron Microscopy

In this paper many of the principal struc­ture of the Moral Lung were studied with the help of Electron Microscopy. Detailed descrip­tion was given of Granular Pneumocytes, Membranous Pneumocytes, Macrophages, and Alveolar Capillaries. A discussion followed on the form and function of Granular Pneumo­cytes.  Acknowledgements  I am grateful to the Reza Shah Pahlavi Foundation for its generou...

Practical aspects of diagnostic electron microscopy.

The electron microscope technique of negative staining was first used to obtain fundamental information about virus morphology, but in recent years it has developed into a practical method for virus diagnosis. The methods employed are both simple and rapid. The following review discusses in detail the steps that must be taken to obtain good electron microscope preparations and illustrates some ...

Quality standards for diagnostic electron microscopy.

Stirling JW, Woods A. Transmission electron microscopy: diagnostic applications. In: Bancroft JD, Gamble M, eds. Theory and Practice of Histological Techniques, 5th ed. London: Churchill Livingstone; 2002:701-728. JOHN W STIRLING Principal Medical Scientist, Electron Microscope Unit, Anatomical Pathology, Flinders Medical Centre, Bedford Park SA 5042 Australia and Co-Convener RCPA QAP EM progra...